Platelet poor plasma is prepared from a patient’s own blood and used to establish a fibrin-rich clot in wounds to enhance rapid and natural healing. PPP also helps generate muscle cell regrowth. This process is one of many techniques that are generally classified as biologic technology. These treatments use the body’s natural healing power to optimize a full recovery.

Benefits of Platelet Poor Plasma

To put it as simply as possible, platelet poor plasma enhances the body’s ability to generate differentiated muscle cells or “myoblasts.” This differentiation is necessary for muscle regeneration and repair.

PPP contains elevated levels of fibrinogen, a glycoprotein that circulates in the blood. In a wound environment, fibrinogen is transformed into a super-rich substance called fibrin that forms a clot that enables healthy cell migration and attachment. Wound bleeding is staunched, and the process of regenerating new muscle is activated. PPP therapy has also been used as for rapid and successful post-surgery healing.

Older man riding a bike

How do I prepare for a PPP injection?

Discontinue any anti-inflammatory medications (e.g. Ibuprofen, Advil, Aleve, Motrin, Aspirin, Celebrex, Voltaren, Mobic, etc) or supplements (Tumeric, Curcumin, Ginger, Fish oil, etc) five days prior to your procedure. If there is a medical reason to be on these medications, discuss this with the physician prior to the treatment. Drink fluids the night and morning before the injection to allow for an adequate blood draw.

What can I expect on the day of the procedure?

Expect to be in clinic for one to one and a half hours. Paperwork will need to be completed prior to your injection. A blood draw from your arm will be performed and this blood will be processed immediately afterwards. The PPP will be administered the same day via injection to the affected area using ultrasound guidance in the clinic. Depending on your injury, an orthosis may be administered followed by any prescriptions including physical therapy. A follow-up appointment will be made at this time as well.

What can I expect after my procedure?

PPP can initiate a healing response and the first phase of healing involves inflammation. As a result, PPP may initially cause stiffness and mild swelling that can potentially last for up to one week. Anti-inflammatory medications are discouraged for up to two weeks after the procedure to allow for an adequate natural inflammatory response. Ice, acetaminophen (Tylenol), and prescribed pain medications can be used if necessary. Activity involving the injured body part as well as flying travel is discouraged during the first week for precautionary reasons. Physical therapy can begin one week after the PPP treatment..

Combination biologic therapy

PPP is often administered in combination with platelet rich plasma to deliver a rich and comprehensive regenerative stimulation to direct your body through its healing processes.

We tend to think of healing in terms of the simple things such as bandaging and physical therapy, etc. In fact, the body is an amazingly diverse and complex web of chemical and cellular behavior. Each physical component, no matter how small, has a job to do that contributes to health maintenance, damage control and growth continuity.

But as phenomenal the body is as a machine it is unable to handle every variable in an active life. Humans throw it curve balls with their activities, diets, and inherited weaknesses.

Combining PPP with PRP in the proper balance activates stem cells, which are triggered by the damaged cells to replace them. As this process continues, your body heals, and pain fades.

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